RAF Typhoon jets have operated alongside French aircraft in a joint strike on an hidden munitions depot in Syria employed by the IS group, according to the UK's MoD.
The facility, located using reconnaissance, was assessed as storing arms and explosives, the release indicated, and was positioned in mountains just north of the ancient city of Palmyra in Syria's central region.
"Our fighter planes employed laser-guided Paveway IV weapons to hit a number of access tunnels providing entry to the depot... initial indications suggest the strike was effective," officials stated.
There was no indication of any civilian casualties in the attack late on Saturday and all the aircraft returned safely, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
The Islamic State group - referred to as ISIS - established jihadist rule over significant areas in Iraq and Syria prior to its 2019 collapse.
"This operation shows our UK leadership, and determination to stand shoulder to shoulder with our partners, to eradicate any revival of the terrorist group and their violent and radical beliefs in the Middle East," the British Defence Secretary the Defence Secretary stated.
RAF aircraft have carried out surveillance missions over Syria to "forestall any attempted comeback" of IS subsequent to its routing at the battle of Baghuz in 2019, the authorities noted.
"I extend gratitude to every member of the UK armed forces who took part in this mission for their professionalism and their courage," Healey said. "They were part of numerous British personnel on duty over the festive period. This operation, to take out dangerous terrorists who pose a risk to our security, shows how our armed forces are prepared to act, continuously, protecting the UK domestically and strong abroad."
During December, the American forces conducted what it described as a "large-scale strike" on Islamic State objectives in the country, following an attack resulted in the deaths of two US servicemembers and a local interpreter in Palmyra.
The U.N. estimates Daesh still has between 5,000 and 7,000 militants in Syria and Iraq.